Scientists tell in which organ Parkinson’s disease originates

A new study has shown that the path from gut problems to Parkinson’s disease may be shorter than we could have imagined.

We often hear about the importance of a healthy gut – from supporting digestion to strengthening the immune system. However, recent research shows that compromised gut health can play a role in more complex problems, such as Parkinson’s disease, New Atlas writes.

Parkinson’s disease (PD) affects nerve cells in the brain, leading to motor and cognitive impairment. Several years before these symptoms appear, protein clots – the so-called Lewy bodies – form in the brain. Researchers have found that these clots also appear in the nervous system of our intestines.

This coincidence led to a theory: could PD actually start in the gut and move to the brain, just as problems with the foundation of a house can eventually lead to problems with the roof? To find out, experts at the Mayo Clinic in Arizona studied the medical records of tens of thousands of people.

Key findings of this study:

  • Four bowel conditions matter: People with gastroparesis (when the stomach empties too slowly), dysphagia (trouble swallowing), constipation, or a special type of irritable bowel syndrome (without diarrhea) are more likely to be diagnosed with Parkinson’s disease. Constipation, gastroparesis, and dysphagia even doubled the risk.
  • No apparent link to certain diseases: Diseases such as inflammatory bowel disease have not been shown to be at increased risk of developing CP. Interestingly, however, they were often found in people who later developed Alzheimer’s disease or cerebrovascular disease.
  • Appendectomy may be protective: Those who had their appendix removed had a lower risk of developing CP. This makes us think about the role of the appendix in the development of Parkinson’s disease.

Despite the significance of this study, it should be remembered that the discovery of a link between gut health and Parkinson’s disease does not mean that one causes the other. Think of it as if you noticed that people often appear with umbrellas when it rains. The presence of an umbrella is not always a consequence of rain, but these two phenomena are often related. In addition, there are some gaps in the study: the observation period was not very long, and the medical record data may be incomplete.

However, the conclusions are self-evident. If you or someone you know has one of these bowel conditions, it does not mean that Parkinson’s is inevitable. But it may be a signal worth paying attention to, perhaps for early detection and assistance.

The researchers believe that understanding this connection can lead to improved methods of diagnosing PD. However, much remains to be discovered about the mysterious connection between the gut and the brain. Research continues to shed light on this strange link in our brain’s functioning, providing clearer answers. In the meantime, this is another reminder of the interconnectedness of our body systems. Taking care of the intestines, whether through diet, exercise, or medical procedures, is not just about digestion. The health and future of our brain potentially depends on it.

This material is for informational purposes only and does not contain advice that may affect your health. If you experience problems, contact a specialist.

Source newatlas
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